Immune response also connects autism and epilepsy

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A Review of Autism and the Immune Response

The autistic spectrum disorders (ASD) are complex developmental disorders that manifest during childhood. By definition, children with ASD are characterized by qualitative impairments in social interaction, deficits in verbal and non-verbal communication, and with restricted repetitive and stereotyped patterns of behavior and interests (American Psychiatric Association, 1994). ASD describes a r...

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Autism and epilepsy: historical perspective.

Autism spectrum disorders (ASD) and epilepsy co-occur in approximately 30% of individuals with either ASD or epilepsy. While there is no single unifying ASD-epilepsy phenotype, understanding potential commonalities in subgroups of children with an ASD-epilepsy phenotype will help us disentangle the pathophysiology of both ASD and epilepsy. Throughout this brief historical perspective we selecti...

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GABR genes, Autism Spectrum Disorder, and Epilepsy

Is there any link between autism and epilepsy? We can shed light on this question by taking a look at which genes are usually associated with both neurological disorders, and asking: are there genes commonly deregulated between them? An interesting fact is that, in general, children with autism are also at higher risk of suffering from certain types of seizures. The role of GABAA receptors (GAB...

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Epilepsy in autism: features and correlates.

BACKGROUND Epilepsy occurs in a significant minority of individuals with autism, but few long-term follow-up studies have been reported, so the prevalence, features (type of seizures, age at onset and severity, etc.) and correlates (IQ history of regression, family history) have only partially been identified. AIMS To undertake a long-term follow-up study of individuals with autism in or...

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ژورنال

عنوان ژورنال: Nature Medicine

سال: 2011

ISSN: 1078-8956,1546-170X

DOI: 10.1038/nm.2445